A new documentary, “End of the Cycle,” is changing the conversation about endometriosis, a condition affecting over 265 million women worldwide. Directed by Sammy Jaye and Soraya Simi, the film weaves together personal narratives, scientific insights, and cultural commentary to challenge decades of misconceptions about the disease. The documentary features a talented ensemble of women living with endometriosis, including comedian Amy Schumer, U.S. Olympian Brittany Brown, and actress Janel Parrish, who share their experiences and describe the condition as “agony, isolation, and harm.” The film also profiles 20th-century icon Marilyn Monroe, who struggled with endometriosis until her death at 36. In addition to patient stories, the documentary features leading researchers and clinicians, including MIT Professor Linda Griffith, director of the Center for Gynepathology Research at MIT. Griffith, who has lived with endometriosis, brings her scientific expertise and personal perspective to the film, highlighting the need for further research and understanding of the condition. The documentary aims to spark action, resilience, and hope, and to encourage investment in research and medical accountability. By sharing personal stories and cutting-edge science, “End of the Cycle” is shedding light on endometriosis and working to break down the stigma surrounding the disease.